Figure 3.

Initial lung cytokine response to injury is normal in obese mice, but early neutrophilia is decreased. BAL cytokine (A, C) and neutrophil (B, D) levels 2 hours after nebulized LPS exposure in lean compared with genetically obese (db/db) and diet-induced obese mice were determined by Bio-Plex and cell counter, respectively. n = 6 mice/condition. *P < 0.05. KC = keratinocyte cytokine; MCP-1 = monocyte chemotactic protein 1; MIP-2 = macrophage inflammatory protein; ns = not significant; PMN = polymorphonuclear leukocyte.