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The parameters derived by fitting equations A5 + A6 to the CCL17 and CCL22 concentration-response curves in the [35S]GTPγS binding experiments at different GDP concentrations
| Parameter | Estimate |
|---|---|
| Emax (103 ccpm) | 16.3 ± 2.1 |
| CCL17 pKa | 8.28 ± 0.09 |
| CCL22 pKa | 8.48 ± 0.07 |
| CCL17 logε | 1.02 ± 0.03 |
| CCL22 logε | 1.53 ± 0.05 |
| Logχ1 | −0.13 ± 0.07 |
| logχ2 | 0.16 ± 0.05 |
| log m | −0.07 ± 0.01 |
| basal (103 ccpm) | 0.68 ± 0.21 |
| log KGDP | −6.26 ± 0.09 |
| log s | −0.11 ± 0.03 |
Data are presented as mean ± SEM.
