Table 7.
Summary of the parameters (derived from equation 1) of the concentration-response curves to CCL17 and CCL22
| Agonist | pEC50 | Emax* | basal | n |
|---|---|---|---|---|
| CCL17 | 9.77 ± 0.09 | 0.94 ± 0.05 | 1.01 ± 0.02 | 1.24 (1.06, 1.44) |
| CCL22 | 9.80 ± 0.12 | 1.06 ± 0.05 | 1.03 ± 0.02 | 1.60 (1.35, 1.90) |
Using equation 1, the upper asymptote of the curves is Emax+basal.
Values are the mean ± SEM of four determinations in separate donors except for n, which is presented as geometric mean with 95% confidence interval in parentheses.