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. 2012 Jul;166(6):1822–1832. doi: 10.1111/j.1476-5381.2012.01891.x

Figure 2.

Figure 2

(A) Protocol employed for studying the effect of cetirizine on OA-induced bronchoconstriction. Also the same timings were used to study vehicle, SB-705498, PF-04065463 or atropine on histamine-induced bronchoconstriction. (B) Protocol employed for studying the responsiveness to a subthreshold aerosol of histamine before and after OA. Treatment 1 h before OA, 2.5 h before histamine with vehicle, SB-705498, PF-04065463, atropine or salbutamol in upper panel. Treatment after OA (1 h before histamine) with vehicle, atropine or SB-705498 in lower panel.