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. 2012 Jul;166(6):1905–1915. doi: 10.1111/j.1476-5381.2012.01895.x

Figure 1.

Figure 1

Effects of AICAR on serum creatinine (A) and serum urea concentrations (B) in rats with RI/R injury. Sham denotes sham-operated rats; RIR, rats with renal I/R injury; RIR + AICAR50, rats with I/R injury treated with AICAR at the dose 50 mg·kg−1 i.v.; RIR + AICAR160, rats with I/R injury treated with AICAR at the dose 160 mg·kg−1 i.v.; RIR + AICAR500, rats with I/R injury treated with AICAR at the dose 500 mg·kg−1 i.v. AICAR, 5-amino-4-imidazolecarboxamide riboside-1-β-D-ribofuranoside. Means ± SEM are given, n= 8–19 in each group. *P < 0.05 versus sham; #P < 0.05 versus RIR; P < 0.05 versus RIR+AICAR50.