Figure 3.
Effects of AICAR on monocyte/macrophage infiltration (ED1-immunopositive cells) in rats with RI/R injury. Representative photomicrographs from untreated rats with I/R injury (A), sham-operated rats (B) and rats with I/R injury treated with 500 mg·kg−1 AICAR (C) are given. Magnification × 200, scale bar 100µm. Quantification of ED1-positive cells in the kidney is presented in (D). Means ± SEM are given, n= 8–19 in each group. *P < 0.05 versus sham; #P < 0.05 versus RIR. For abbreviations, see Figure 1 legend.