Table 6.
Parameter modified | Value in BC | Value in SA | Scenario without B/N combination | Scenario with B/N combination | Difference (€) with B/N vs. without B/N | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|
1st year | 2nd year | 3rd year | 1st year | 2nd year | 3rd year | 1st year | 2nd year | 3rd year | |||
Transition probabilities | See table 1 | Same values for B/N combination than used for methadone | 1,102 | 1,026 | 1,017 | 1,113 | 1,035 | 1,028 | 10.58 | 9.18 | 11.13 |
B/N combination uptakes | 10%, 15% and 20% for 1st, 2nd and 3rd year | 0.97%; 2.57% and 3.83% for 1st, 2nd and 3rd year | 1,102 | 1,026 | 1,017 | 1,103 | 1,028 | 1,019 | 1.03 | 1.37 | 1.58 |
Initial proportion of patient distribution | HTP: 30% and LITP: 70% | HTP: 100% | 1,477 | 1,185 | 1,127 | 1,513 | 1,204 | 1,144 | 35.260 | 19.13 | 16.46 |
LITP: 100% | 941 | 958 | 970 | 941 | 960 | 973 | 0 | 1.76 | 3.44 | ||
Resource cost (cost per minute) | See table 3 | +10% | 1,201 | 1,126 | 1,116 | 1,218 | 1,129 | 1,119 | 7.78 | 2.87 | 2.30 |
-10% | 995 | 926 | 918 | 1,008 | 937 | 930 | 13.38 | 11.08 | 12.39 |
Yearly budgetary impact per patient (€, 2010)
BC: Base Case; SA: Sensitivity analysis