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. 2012 Aug 15;139(16):3032–3039. doi: 10.1242/dev.075812

Fig. 6.

Fig. 6.

RTK signaling promotes wntD expression via relief of Groucho- and Capicua-dependent repression. (A-C) Stage 4 wild-type (A), gro (B) and cic maternal mutant (C) embryos, hybridized using a digoxigenin-labeled wntD RNA probe. There is ventral expansion of wntD expression in the mutants. (D-I) Stage 5 wild-type (D,G), gro (E,H) and cic mutant (F,I) embryos stained for Dl (green). The reduced accumulation of nuclear Dl in the two mutant backgrounds is evident both in ventral views (E,F; compare with D) and in sagittal cross-sections (H,I; compare with G). (J-L) Stage 5 embryos stained for Vnd (green). Note the weaker expression in gro (K) and cic (L) mutant embryos, compared with wild-type control (J). Embryos are oriented with anterior to the left.