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The relationship between PF-04457845 plasma concentrations and FAAH1 inhibition at doses up to 10 mg PF-04457845 (SRD study), 0.1 mg (●), 0.3 mg (○), 1 mg (▴), 3 mg (▵), 10 mg (
). (Higher doses are entirely compatible with the emergent pattern but are not included as the amount of data at high concentrations obscures the relationship.)
