Table 5.
Serious adverse events judged to be possibly, probably or definitely related to vaccination (i.e. serious adverse reactions)
| Patient gender/age (years) | Follow-up period event reported | Received H1N1 vaccine | Time from vaccination to onset of symptoms (days) | Patient self report of symptoms | Duration of symptoms (days) | Patient sought medical attention | Diagnosis | Treatment received | Symptoms Resolved | Ongoing Treatment | Possible alternative causes | Relatedness |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| M/46 | 2 | Y | 7 | Flu like symptoms 5 days. Admitted to hospital, shortness of breath and productive cough, flushed and sweating | 5 | Y (Hospital doctor) | Lower respiratory tract infection | Antibiotics | Y | N | Viral infection | Possibly |
| F/62 | 2 | Y | 53 | Facial droop | Ongoing at follow-up | Y (GP) | Bell's palsy | Steroids | N | N | NS | Possibly |
| F/59 | 2 | Y | 12 | Epileptic seizure, post-seizure paralysis in right arm and leg for 2 days. Had past history of epilepsy | 5 | Y (Hospital doctor) | Epileptic seizure | Medication NS | Y | Y | NS | Possibly |
| F/71 | 1 | Y | 14 | Severe headaches, admitted to hospital with suspected meningitis. No meningitis found. Diagnosis- chronic migraines | NS | Y (Hospital doctor) | Chronic migraines | NS | NS | NS | NS | Possibly |
| M/39 | 1 | Y | 1 | Pins and needles and numbness in hands, feet, legs and arms. Pins and needles and numbness left side of head, tongue, nose and lips, muscle weakness, poor co-ordination, lack of sleep, slurred speech, dizzy, light headed spells, migraines, extreme tiredness. | NS | Y (Hospital doctor) | Seen by neurologist- suggested nerve fibre damage | NS | NS | NS | NS | Probably |
| F/38 | 1 | Y | 2 | Swelling at injection site, painful and hard. Felt unwell, flu like symptoms. Had three seizures. Admitted to hospital, no history of previous seizures. Had CT scan – normal. Patient had allergy to eggs. Suffered muscular damage during seizures – causing severe back pain. | Ongoing at follow-up | Y (Hospital doctor) | Epileptic seizures | NS | NS | NS | Allergy to eggs | Possibly |
| F/48 | 2 | Y | 32 | Chronic fatigue, dizzy turns | Ongoing at follow-up | Y (GP) | ? Anaemia/ problem with thyroxine concentrations | Medication NS | N | Y | Unknown | Possibly |
| M/57 | 2 | Y | 2 | Pulmonary embolism | 37 days | Y (Hospital doctor) | Pulmonary embolus | Medication NS | Y | Y | Had hernia repair prior to immunisation. | Possibly |
| F/56 | 1 | Y | 6 | Skin inflamed and red, area spreading, then developed white itchy spots in same area | 18 days | Y (Hospital Dr) | Local reaction to vaccine | Antibiotics | Y | N | Vaccine | Definitely |
NS = not specified