Figure 4.

Modeling of bovSERPINA3-3 and bovSERPINA3-7. A: Modeling of dimeric bovSERPINA3-3. The two chains of the dimer are rendered in cartoon mode with in red chain A and blue chain B. The D371 atoms are rendered in sphere and colored in yellow for chain A and in cyan for chain B (Figure drawn with PyMOL 0.99rc6). The aspartate residues of each monomer are involved in the dimeric interface in this model. B: Superposition of the two chains bovSERPINA3-3 (blue) and bovSERPINA3-7 (green). The D371 radical in bovSERPINA3-3 points toward the external face of the molecule. On contrary, the E376 radical in bovSERPINA3-7 points toward hydrophobic core of the molecule.