Table I.

Acyl Carrier Protein Families

Family	Approximate number of sequencesa	Producing domain	Role	Representative end product (nonexhaustive list)	UniProt accession code	Reference
ACP1	2870	B, E, Ab	Freestanding ACPs:
			in type II fatty acid synthesis	Fatty acids	P0A6A8	19
			in bacterial long-chain fatty acid synthesis	Long-chain fatty acids	P0A2W5	20
			in mitochondria	Fatty acids	P52505	21
ACP2	180	E	ACP domains of fungal FASs	Fatty acids	P19097	22
ACP3	190	E	ACP domains of animal FASs	Fatty acids	P49327	23
ACP4	50	B	Freestanding ACPs in polyketide synthesis	Bacillaene	Q7PC63	24
ACP5	100	B	Freestanding ACPs in polyketide synthesis	Actinorhodin	Q02054	25
				Frenolicin	Q54996	26
				Oxytetracycline	P43677	27
ACP6	100	B	ACP domains in PKSs	Mycocerosic acid	Q02251	28
				Phthioceranic acids	O07798	29
ACP7	30	E	ACP domains in PKSs	6-Methylsalicylic acid	P22367	30
ACP8	240	B, E	ACP domains in PKSs	Aflatoxin	Q12053	31
				Conidial yellow pigment	Q03149	32
ACP9	80	E	ACP domain in PKSs/chalcone synthases	Acylpyrones	Q55E72	33
ACP10	7000	B, E, A	ACP/PCP domain in PKSs/NRPSs and ACP domain in ferrichrome synthases	Surfactin	P27206	34
				Erythronolide	Q03131	35
				Gramicidin	P0C061	36
				Phthiocerol	Q7TXL8	37
				Tyrocidine	O30409	38
				Plipastatin	O31827	39
				Enniatin	Q00869	40
				Ferrichrome	Q9P7T1	41
				Bacillaene	Q05470	42
ACP11	120	E	ACP domains in PKSs	Lovastatin	Q9Y8A5	43
ACP12	280	B	ACP domains in enterobactin synthases	Enterobactin	P0ADI4	44
			ACP domains in isochorismatases	Mycobactins	P71717	45
ACP13	220	B, E	ACP domains in enterobactin synthases	Enterobactin	P11454	46
ACP15	200	B	Freestanding ACPs active with malonate  decarboxylases	Acetate	O06925	47
ACP16	300	B	Freestanding ACPs active with citrate lyases	Acetyl-CoA	P02903	48
ACP17	250	B	Freestanding d-alanyl carrier proteins	d-Alanyl lipoteichoic acid	P55153	49

^aPresent in the ThYme database at the time of writing this article.

^bA, archaea; B, bacteria; E, eukaryota. Most prevalent producers bolded.