Table 1.

Kinases and phosphatases regulating phosphorylation of AJ proteins.

Gene symbol	Protein name	Phosphorylation type	Localization	Reference
Kinases
SRC	Proto-oncogene tyrosine-	Tyr	nonreceptor	[23, 30, 31]
	protein kinase Src
CSK	c-src tyrosine kinase	Tyr	nonreceptor	[24, 32, 33]
FYN	Tyrosine-protein kinase Fyn	Tyr	nonreceptor	[34–36]
ABL1	Abl1	Tyr	nonreceptor	[37, 38]
SYK	Tyrosine protein kinase SYK	Tyr	nonreceptor	[39, 40]
PTK2B	Protein-tyrosine kinase 2-beta	Tyr	nonreceptor	[41–43]
FER	Tyrosine-protein kinase Fer	Tyr	nonreceptor	[44]
EGFR	Epidermal growth factor receptor	Tyr	Receptor	[45]
cMET/HGF	Hepatocyte growth factor receptor	Tyr	Receptor	[46]
PRKCA	Protein kinase C alpha type	Ser/Thr	nonreceptor	[47]
PRKACA	cAMP-dependent protein	Ser/Thr	nonreceptor	[48, 49]
	Kinase catalytic subunit alpha
ROCK1	Rho-associated, coiled-coil	Ser/Thr	nonreceptor	[50]
	containing protein kinase 1
PRKCD	Protein kinase C delta type	Ser/Thr	nonreceptor	[51, 52]
CSNK1E	Casein kinase I isoform epsilon	Ser/Thr	nonreceptor	[53]
CSNK2A1	Casein kinase 2	Ser/Thr	nonreceptor	[54]
PAK1	Serine/threonine-protein kinase PAK 1	Ser/Thr	nonreceptor	[55–57]
MAPK8	JNK	Ser/Thr	nonreceptor	[58]
PRKD1	Protein kinase D1	Ser/Thr	nonreceptor	[59]
PRKCI	Atypical protein kinase C-lambda/iota	Ser/Thr	nonreceptor	[60]
PRKCZ	Protein kinase C zeta type	Ser/Thr	nonreceptor	[60]
MARK2	MAP/microtubule affinity-	Ser/Thr	nonreceptor	[61]
	Regulating kinase 2, Par-1
Phosphatases
PTPN1	Tyrosine-protein phosphatase non	Tyr	nonreceptor	[19, 62–64]
	receptor type 1, PTP1B
PTPN6	Tyrosine-protein phosphatase non	Tyr	nonreceptor	[65]
	receptor type 6, SHP1
PTPN11	Tyrosine-protein phosphatase non-	Tyr	nonreceptor	[66]
	receptor type 11, SHP2
PTPN12	Tyrosine-protein phosphatase non-	Tyr	nonreceptor	[67]
	receptor type 12, PTP-PEST
PTPN14	Tyrosine-protein phosphatase non-	Tyr	nonreceptor	[68]
	receptor type 14, PEZ
ACP1	Acid phosphatase of erythrocyte, LMW-PTP	Tyr	nonreceptor	[69, 70]
PTPRJ	Receptor-type tyrosine-protein	Tyr	Receptor	[71]
	phosphatase eta (R-PTP-eta), DEP1
PTPRM	Receptor-type tyrosine-protein	Tyr	Receptor	[72–74]
	phosphatase mu (RPTP mu)
PTPRT	Receptor-type tyrosine-protein	Tyr	Receptor	[75]
	phosphatase T (R-PTP-T)
PTPRU	Receptor-type tyrosine-protein	Tyr	Receptor	[76, 77]
	phosphatase U (R-PTP-U)
PTPRK	Receptor-type tyrosine-protein	Tyr	Receptor	[78, 79]
	phosphatase kappa
PTPRF	Receptor-type tyrosine-protein	Tyr	Receptor	[80–82]
	phosphatase F, LAR
PPP2CA	Serine/threonine-protein phosphatase 2A	Ser/Thr	nonreceptor	[83–85]
	catalytic subunit alpha isoform