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. Author manuscript; available in PMC: 2013 May 1.
Published in final edited form as: Mol Biochem Parasitol. 2012 Feb 11;183(1):1–7. doi: 10.1016/j.molbiopara.2012.02.001

Figure 1. Exogenous serotonin (5-HT) causes an unusual “kinked” paralysis in J2s of the soybean cyst nematode, Heterodera glycines.

Figure 1

J2s were incubated for 20 min in liquid culture with 20 mM 5-HT. These high concentrations of exogenous 5-HT are necessary to overcome the relative impermeability of the nematode cuticle. However, as noted in the text, this paralysis appears to result exclusively from the actions of 5-HT on serotonergic signaling, as locomotion in C. elegans lacking key 5-HT receptors is completely unaffected by 5-HT at these concentrations. We would like to thank Julia Thissen for these unpublished pictures of H. glycines J2s.