Table 2.

Mean (± s.d.) depression and fatigue scores in IFN-α-treated and control subjects

	IFN-α (n = 20)			Control (n = 13)
	Visit 1	Visit 2	Delta	Visit 1	Visit 2	Delta
MADRS	3.3 (3.6)	13.3 (10.4)*†	10.0 (9.8)	3.8 (5.0)	3.2 (3.6)	−0.6 (2.7)
MFI
Total	37.2 (10.3)	61.2 (21.7)*,†	24.0 (18.5)	42.2 (14.9)	37.5 (15.3)	−4.7 (6.8)
GF	8.9 (3.2)	14.2 (4.6)*†	5.3 (4.3)	10.3 (4.0)	8.5 (3.9)	−1.8 (2.3)
PF	8.3 (3.4)	13.3 (4.5)*†	5.0 (3.9)	9.0 (3.3)	8.8 (3.8)	−0.2 (1.7)
RA	6.7 (2.6)	12.4 (4.9)*†	5.7 (4.2)	8.1 (3.4)	6.8 (3.4)	−1.2 (1.3)
RM	6.7 (2.4)	11.5 (4.6)*†	5.7 (4.2)	7.2 (3.0)	6.5 (2.6)	−1.2 (1.3)
MF	6.7 (2.5)	9.9 (5.2)*†	3.3 (4.7)	7.6 (3.4)	6.8 (3.7)	−0.8 (2.1)

Abbreviations: GF, general fatigue; PF, physical fatigue; MADRS, Montgomery–Asberg depression rating scale; MF, mental fatigue; MFI, multidimensional fatigue inventory; RA, reduced activity; RM, reduced movement; s.d., standard deviation.

^*Significantly different from visit 1 (P < 0.05 using Student-Newman-Keuls method).

^†Significantly different from respective control value (P < 0.05 using Student-Newman-Keuls method).