. Author manuscript; available in PMC: 2012 Jul 24.

Published in final edited form as: Mol Psychiatry. 2008 Jun 3;15(5):535–547. doi: 10.1038/mp.2008.58

Table 4.

Mean (± s.d.) cytokines and cytokine receptors in IFN-α-treated and control subjects

	IFN-α (n = 20)			Control (n = 13)
	Visit 1	Visit 2	Delta	Visit 1	Visit 2	Delta
Cytokines (pg ml⁻¹
IFN-α^‡	11.7 (11.3)	44.2 (28.9)^*^†	32.4 (29.7)	9.6 (11.0)	12.8 (25.7)	3.2 (19.5)
TNF-α	1.7 (0.85)	2.1 (0.96)	0.4 (0.6)	1.7 (1.0)	1.7 (1.0)	0.0 (0.3)
IL-6	4.9 (3.9)	4.6 (4.2)	−0.4 (4.8)	4.0 (2.1)	4.4 (2.0)	0.4 (2.3)
Soluble receptors (ng ml⁻¹)
sTNF-RII	2.8 (1.7)	3.6 (1.6)^*,^†	0.8 (0.7)	2.4 (1.2)	2.5 (1.2)	0.1 (0.4)
sIL-6R	33.8 (8.3)	33.4 (9.0)	−0.4 (4.8)	32.4 (7.2)	32.1 (7.4)	−0.3 (1.7)

Abbreviations: IL-6, interleukin-6; sIL-6R, soluble interleukin-6 receptor; s.d., standard deviation; sTNF-RII, soluble tumor necrosis factor receptor; TNF, tumor necrosis factor.

Significantly different from visit 1 (P < 0.05 using Student-Newman-Keuls method).

^†

Significantly different from respective control value (P < 0.05 using Student-Newman-Keuls method).

^‡

Only subjects taking IFN-α 2b were included in these analyses.