Table 2.
Exposure (h)/±S9 | Dose (μg mL−1) | Structural aberrations | Numerical aberrations | Cell growth (%) | ||
---|---|---|---|---|---|---|
Chromatid break | Chromatid exchange | Polyploidy | Endoreduplication | |||
6/+S9 | 0 | 1 | 0 | 1 | 0 | 100 |
150 | 2 | 0 | 1 | 0 | 99.2 | |
300 | 2 | 0 | 1 | 0 | 98.3 | |
600 | 1 | 0 | 0 | 0 | 99.4 | |
1250 | 2 | 0 | 1 | 0 | 98.5 | |
2500 | 1 | 0 | 0 | 0 | 99.1 | |
5000 | 3 | 1 | 1 | 0 | 97.8 | |
B[a]P 0.2 | 25 | 37 | 6 | 2 | 61.3 | |
| ||||||
6/−S9 | 0 | 1 | 0 | 0 | 0 | 100 |
150 | 3 | 0 | 2 | 0 | 99.3 | |
300 | 3 | 0 | 1 | 0 | 98.2 | |
600 | 2 | 0 | 1 | 0 | 97.6 | |
1250 | 2 | 0 | 1 | 0 | 98.1 | |
2500 | 3 | 0 | 0 | 0 | 97.4 | |
5000 | 3 | 1 | 0 | 0 | 96.5 | |
B[a]P 0.15 | 25 | 36 | 5 | 2 | 57.2 | |
| ||||||
24/−S9 | 0 | 0 | 0 | 1 | 0 | 100 |
150 | 4 | 0 | 1 | 0 | 99.3 | |
300 | 3 | 0 | 2 | 0 | 97.9 | |
600 | 1 | 0 | 0 | 0 | 98.2 | |
1250 | 2 | 0 | 1 | 0 | 96.8 | |
2500 | 1 | 0 | 0 | 0 | 97.4 | |
5000 | 3 | 0 | 2 | 0 | 98.6 | |
MMC 0.05 | 36 | 44 | 3 | 1 | 62.3 | |
| ||||||
48/−S9 | 0 | 0 | 0 | 1 | 100 | |
150 | 0 | 0 | 0 | 0 | 99.6 | |
300 | 1 | 0 | 1 | 0 | 98.2 | |
600 | 3 | 0 | 1 | 0 | 98.1 | |
1250 | 3 | 0 | 0 | 0 | 97.9 | |
2500 | 1 | 0 | 0 | 0 | 98.2 | |
5000 | 1 | 0 | 1 | 0 | 97.6 | |
MMC 0.05 | 26 | 0 | 4 | 1 | 60.4 |