. Author manuscript; available in PMC: 2012 Jul 24.

Published in final edited form as: Hum Genet. 2010 Nov 23;129(2):221–230. doi: 10.1007/s00439-010-0917-1

Table 3. Discriminative accuracy of genetic risk sum score and covariates predicting BMI category.

Group	n (%)	AUC [CI]	Asy. Sig.
Overweight	2,157 (71.1)	0.613 [0.591,0.635]	1.21E−22
Obese 1	1,139 (37.5)	0.588 [0.567,0.610]	3.11E−16
Obese 2	519 (17.1)	0.647 [0.621,0.673]	5.32E−26
Obese 3	232 (7.6)	0.697 [0.663,0.731]	1.75E−23

Predictors included in models: molecularly derived ancestry (principal components PC1 and PC4), sex, age, PC1 by sex and PC4 by sex interactions and genetic risk sum score

BMI body mass index (kg/m²), AUC area under the receiver operator criteria curve, Asy. Sig. asymptotic significance, Overweight BMI > 25 kg/m², Obese I BMI > 30 kg/m², Obese II BMI > 35 kg/m², Obese III BMI > 40 kg/m²