Table 3.
Odds Ratios for Incident Rheumatoid Arthritis by Baseline Periodontal and Tooth Loss Status: Longitudinal Results from The First National Health and Nutrition Examination Survey and Its Epidemiologic Follow-up Study (n=9,564; 433 RA cases)
| Periodontal Status
| |||||
|---|---|---|---|---|---|
| Healthy Periodontium | Gingivitis | Periodontitis | Edentulous | ||
| Reference *(PI<0.05) | * PI=(1.36±0.03) | *(PI=4.45±0.04) | |||
| RA incidence (n=139/3379; 4.1%) | RA incidence (n=97/2169; 4.5%) | RA incidence (n=79/1727; 4.6%) | RA incidence (n=118/2289; 5.2%) | ||
| 1. | 1.0 | 1.32(0.86,2.01) | 1.12(0.79,1.58) | 1.34(0.90,1.99) | |
| 2. | 1.0 | 1.33(0.85,2.06) | 1.01(0.68,1.49) | 0.99(0.65,1.53) | |
| 3. | 1.0 | 1.29(0.84,1.99) | 0.96(0.63,1.45) | 0.96(0.62,1.47) | |
| 4. | 1.0 | 1.32(0.85,2.06) | 1.00(0.68,1.48) | 1.00(0.65,1.52) | |
| 5. | 1.0 | 1.37(0.87,2.17) | 1.05(0.70,1.58) | 1.02(0.66,1.58) | |
|
| |||||
|
Tooth Loss
| |||||
| 0–4 MT | 5–8 MT | 9–14 MT | 15–31 MT | Edentulous | |
| *(PI=0.71±0.03) | *(PI=1.01±0.04) | *(PI=1.77±0.05) | *(PI=2.56±0.06) | ||
| RA incidence (n=63/2003; 3.2%) | RA incidence (n=80/1952; 4.1%) | RA incidence (n=89/1533; 5.8%) | RA incidence (n=83/1787; 4.6%) | RA incidence (n=118/2289; 5.2%) | |
| 1. | 1.0 | 1.29(0.86,1.92) | 2.07(1.43,3.00) | 1.81(1.18,2.78) | 1.74(1.08,2.81) |
| 2. | 1.0 | 1.13 (0.77,1.64) | 1.68(1.13,2.49) | 1.41(0.85,2.33) | 1.22(0.75,2.00)** |
| 3. | 1.0 | 1.11 (0.75,1.64) | 1.77(1.18,2.66) | 1.43(0.86,2.39) | 1.23(0.73,2.06) |
| 4. | 1.0 | 1.12(0.77,1.64) | 1.67(1.12,2.48) | 1.40(0.85,2.33) | 1.22(0.75,2.00) |
| 5. | 1.0 | 1.02(0.67,1.56) | 1.71(1.14,2.56) | 1.45(0.87,2.42) | 1.23(0.72,2.04) |
1
crude
2
adjusted for age, sex, race, education, smoking
3
model 2 + pack years (sample size reduced to 8,466, 412 RA cases)
4
model 2 + body mass index and physical activity level (no activity, moderately active, very active)
5
model 4 + poverty index (sample size reduced to 9,221, 413 RA cases)
*
Mean periodontal index±standard error per periodontal status or tooth loss category
**
p-value for comparison with 9–14 missing teeth = 0.14