Table 5.
Gene ontology and pathway enrichment in R+ versus C+ 5HT neurons
| Code | Gene set name | Size | Bon |
|---|---|---|---|
| R+ molecular function-enriched gene sets | |||
| 346 | Substrate-specific transmembrane transporter activity | 152/308 | 0.02889313 |
| 271 | Protein kinase activity | 129/264 | 0.00560058 |
| 347 | Substrate-specific transporter activity | 167/347 | 0.00245254 |
| 163 | Kinase activity | 156/342 | 0.00065897 |
| 328 | Small GTPase regulator activity | 21/64 | 0.00779472 |
| C+ biological process-enriched gene sets | |||
| 62 | Calcium ion transport | 15/24 | 0.00074155 |
| 168 | Di-, trivalent inorganic cation transport | 18/29 | 0.00021683 |
| 800 | Transport | 392/703 | 0.00019125 |
| 246 | G-protein-coupled receptor protein signaling pathway | 114/290 | 3.6497 × 10−5 |
| C+ molecular function-enriched gene sets | |||
| 18 | Aminopeptidase activity | 8/10 | 0.00490194 |
| 174 | Lipid kinase activity | 8/11 | 0.03140293 |
| 38 | Calcium channel activity | 19/30 | 0.01250318 |
| 118 | GTPase regulator activity | 77/122 | 0.00713664 |
| 279 | Protein serine threonine kinase activity | 116/189 | 2.405 × 10−5 |
| 168 | Ligand-gated channel activity | 17/32 | 0.00144691 |
| 384 | Transmembrane transporter activity | 174/338 | 0.01154298 |
| 188 | Metal ion transmembrane transporter activity | 66/131 | 0.00658676 |
Bon, Bonferroni-corrected p value.