Table 2.
Sensitivity, specificity, positive predictive value, negative predictive value, accuracy, and kappa measure of agreement of rapid immunochromatography test compared with fluorescent antibody test for detection of rabies virus*
| Characteristic | Country | ||||
|---|---|---|---|---|---|
| Thailand | Bhutan | Sri Lanka | Sri Lanka | Sri Lanka | |
| Species | Dog | Cow, dog | Cat | Other animals | Human |
| No. samples | 228 | 27 | 115 | 47 | 86 |
| Sensitivity | 0.95 (0.89–0.98) | 0.90 (0.70–0.99) | 0.74 (0.57–0.87) | 0.89 (0.52–1.0) | 0.99 (0.93–1.0) |
| Specificity | 0.98 (0.93–1.0) | 1.0 (0.54–1.0) | 1.0 (0.95–1.0) | 1.0 (0.91–1.0) | 0.08 (0.0–0.38) |
| PPV | 0.98 (0.94–1.0) | 1.0 (0.82–1.0) | 1.0 (0.88–1.0) | 1.0 (0.63–1.0) | 0.87 (0.78–0.93) |
| NPV | 0.94 (0.88–1.0) | 0.75 (0.35–0.97) | 0.88 (0.80–0.94) | 0.97 (0.86–1.0) | 0.50 (0.01–0.99) |
| Accuracy | 0.96 (0.93–0.98) | 0.93 (0.74–0.99) | 0.91 (0.82–0.96) | 0.98 (0.83–1.0) | 0.86 (0.74–0.93) |
| KMA | 0.93 (0.88–0.98), Very good | 0.81 (0.55–1.06), Very good | 0.79 (0.66–0.91), Good | 0.93 (0.79–1.07), Very good | 0.17 (–0.36 to 0.58), Poor |
*Values in parentheses are 95% confidence intervals. PPV = positive predictive value; NPV = negative predictive value; KMA = kappa measure of agreement.