Table 1.
Spot | Protein Name | Accession Number | Molecular Weight (Da) | Change in Prefrail* | Peptides Searched | Peptides Matched | Percent Coverage | Mowse Score |
1 | Complement factor H | P08603 | 139,019 | — | 36 | 20 | 17 | 98 |
2 | Complement factor B | P00751 | 85,479 | — | 19 | 9 | 11 | 68 |
3 | Thrombin | P00734 | 69,209 | — | 32 | 13 | 20 | 90 |
4 | Transferrin | P02787 | 77,050 | ↑ | 19 | 10 | 18 | 75 |
5 | Alpha-1-b-glycoprotein | P04217 | 51,908 | — | 36 | 12 | 27 | 94 |
6 | Hemopexin | P02790 | 51,643 | — | 25 | 15 | 35 | 152 |
7 | Complement component C3 | P01024 | 71,146 | — | 26 | 19 | 36 | 205 |
8 | Serum albumin | P02768 | 69,349 | — | 36 | 21 | 34 | 148 |
9 | Olfactomedin-like 3 | Q9NRN5 | 46,101 | — | 18 | 7 | 18 | 56 |
10 | Olfactomedin-like 3 | Q9NRN5 | 46,101 | — | 16 | 7 | 22 | 67 |
11 | Alpha-1 antitrypsin | P01009 | 46,678 | — | 27 | 10 | 30 | 89 |
12 | Chain C fibrinogen gamma | P02679 | 51,512 | — | 10 | 5 | 17 | 60 |
13 | Chain C fibrinogen gamma fragment D | P02679 | 36,157 | — | 11 | 7 | 24 | 92 |
14 | Haptoglobin | P00738 | 45,205 | — | 8 | 5 | 16 | 69 |
15 | Haptoglobin | P00738 | 45,205 | — | 20 | 8 | 31 | 75 |
16 | Serum amyloid | P02743 | 23,244 | — | 20 | 7 | 29 | 82 |
17 | Apolipoprotein A1 | P02647 | 28,061 | — | 50 | 19 | 61 | 189 |
Notes: *Up arrow (↑) indicates glycoprotein was increased and down arrow (↓) indicates glycoprotein was decreased in prefrail compared with nonfrail older adults. Dash (—) indicates no change.