Table 4.

MMSE Cutoff Scores for Detection of MCI/Probable and Possible AD by Ethnicity

	Cut Score	Sensitivity (95% CI)	Specificity (95% CI	Likelihood Ratio	False-Positive Rate	False-Negative Rate
All ethnicities	24	0.38 (0.36–0.39)	1.00 (0.99–1.00)	97.24	13	2333
	25	0.44 (0.42–0.45)	0.99 (0.99–0.99)	55.87	26	2121
	26	0.51 (0.49–0.52)	0.98 (0.98–0.99)	26.42	64	1853
	27	0.59 (0.57–0.60)	0.96 (0.95–0.96)	14.02	140	1547
	28	0.67 (0.66–0.69)	0.90 (0.89–0.91)	6.78	332	1221
African American	24	0.42 (0.36–0.48)	0.98 (0.96–0.99)	26.66	5	153
	25	0.46 (0.40–0.53)	0.97 (0.95–0.99)	16.54	9	140
	26	0.52 (0.46–0.58)	0.94 (0.91–0.96)	8.72	19	126
	27	0.61 (0.55–0.67)	0.87 (0.83–0.91)	4.86	40	102
	28	0.69 (0.64–0.75)	0.79 (0.74–0.83)	3.28	67	81
Asian	24	0.40 (0.30–0.52)	1.00	––	0	50
	25	0.45 (0.34–0.56)	1.00	––	0	46
	26	0.57 (0.46–0.68)	0.98 (0.92–1.00)	37.14	1	36
	27	0.61 (0.49–0.71)	0.98 (0.92–1.00)	39.46	1	33
	28	0.72 (0.62–0.82)	0.89 (0.79–0.96)	6.74	7	23
Hispanic (all)	24	0.44 (0.34–0.54)	0.96 (0.90–0.99)	12.43	3	55
	25	0.48 (0.38–0.58)	0.94 (0.87–0.98)	8.15	5	51
	26	0.56 (0.46–0.66)	0.94 (0.87–0.98)	9.54	5	43
	27	0.70 (0.60–0.79)	0.92 (0.84–0.97)	8.55	7	29
	28	0.79 (0.69–0.86)	0.86 (0.77–0.92)	5.57	12	21
Mexican American	24	0.36 (0.18–0.57)	1.00	––	0	16
	25	0.40 (0.21–0.61)	1.00	—	0	25
	26	0.48 (0.28–0.69)	1.00	––	0	13
	27	0.68 (0.46–0.85)	1.00	––	0	8
	28	0.76 (0.55–0.91)	0.96 (0.78–1.00)	17.48	1	6
White	24	0.37 (0.36–0.39)	1.00	156.73	7	2106
	25	0.43 (0.41–0.45)	0.99 (0.99–1.00)	79.00	16	1914
	26	0.50(0.49–0.52)	0.98 (0.98–0.99)	34.29	43	1672
	27	0.59 (0.57–0.60)	0.97 (0.96–0.97)	18.06	95	1395
	28	0.67 (0.66–0.69)	0.91 (0.90–0.92)	7.78	253	1103

Note : AD = Alzheimer's disease; CI = confidence interval; MCI = mild cognitive impairment; and MMSE = Mini-Mental State Examination.