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RBP-4 isoform 1 is decreased as a function of age only in WT female mice. Two-way analysis of variance with repeated measures revealed a significant interaction between age and sex: F(2,36) = 8.5, p = .001, as well as a significant interaction between genotype and sex: F(1,18) = 8.3, p = .01. RBP-4 = retinol-binding protein-4; WT = wild-type.
