Table 1.
OHSS stage | Clinical features | Laboratory features |
---|---|---|
Mild |
Abdominal distension/discomfort |
No important alterations |
Mild nausea/vomiting | ||
Diarrhea | ||
Enlarged ovaries | ||
Moderate |
Mild features + |
Elevated hematocrit (>41 %) |
Ultrasonographic evidence of ascites |
Elevated WBC (>15000) |
|
|
Hypoproteinemia |
|
Severe |
Mild and moderate features + |
Hemoconcentration (Hct >55 %) |
Clinical evidence of ascites |
WBC >25000 |
|
Hydrothorax |
CrCl <50 mL/min |
|
Severe dyspnea |
Cr >1.6 |
|
Oliguria/anuria |
Na+ <135 mEq/L |
|
Intractable nausea/vomiting |
K+ >5 mEq/L |
|
Tense ascites |
Elevated liver enzymes |
|
Low blood/central venous pressure |
|
|
Rapid weight gain (>1 kg in 24 hours) |
|
|
Syncope |
|
|
Severe abdominal pain |
|
|
Venous thrombosis |
|
|
Critical | Anuria/acute renal failure |
Worsening of findings |
Arrhythmia | ||
Thromboembolism | ||
Pericardial effusion | ||
Massive hydrothorax | ||
Arterial thrombosis | ||
Adult respiratory distress syndrome | ||
Sepsis |
Cr = serum creatinine level; CrCl = creatinine clearance; WBC = white blood cell count.