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. 2012 Apr 24;10:32. doi: 10.1186/1477-7827-10-32

Table 1.

Classification of OHSS symptoms[5] (adapted from Navot et al [9])

OHSS stage Clinical features Laboratory features
Mild
Abdominal distension/discomfort
No important alterations
Mild nausea/vomiting
Diarrhea
Enlarged ovaries
Moderate
Mild features +
Elevated hematocrit (>41 %)
Ultrasonographic evidence of ascites
Elevated WBC (>15000)
 
Hypoproteinemia
Severe
Mild and moderate features +
Hemoconcentration (Hct >55 %)
Clinical evidence of ascites
WBC >25000
Hydrothorax
CrCl <50 mL/min
Severe dyspnea
Cr >1.6
Oliguria/anuria
Na+ <135 mEq/L
Intractable nausea/vomiting
K+ >5 mEq/L
Tense ascites
Elevated liver enzymes
Low blood/central venous pressure
 
Rapid weight gain (>1 kg in 24 hours)
 
Syncope
 
Severe abdominal pain
 
Venous thrombosis
 
Critical Anuria/acute renal failure
Worsening of findings
Arrhythmia
Thromboembolism
Pericardial effusion
Massive hydrothorax
Arterial thrombosis
Adult respiratory distress syndrome
Sepsis

Cr = serum creatinine level; CrCl = creatinine clearance; WBC = white blood cell count.