Table 3.
Levels of organochloride residues (ng/g lipid) detected in serum samples in healthy women and in women diagnosed from breast cancer older than 45 years old
| |
Healthy women (n = 49) |
Breast cancer women (n =105) |
|
||||
|---|---|---|---|---|---|---|---|
| Mean ± SD | Median (p5-p95) | D (%) | Mean ± SD | Median (p5-p95) | D (%) | P | |
| Lindane |
16.6 ± 34.6 |
0.0 (0.0-104.5) |
10 (20.4%) |
49.5 ± 85.4 |
0.0 (0.0-215.2) |
27 (25.7%) |
n.s.a n.s.b |
| Aldrin |
15.0 ± 27.5 |
0.0 (0.0-73.2) |
12 (24.5%) |
71.7 ± 114.3 |
74.8 (0.0-115.7) |
76 (72.4%) |
<0.001 a <0.001 b |
| Dieldrin |
7.0 ± 16.0 |
0.0 (0.0-49.7) |
10 (20.4%) |
12.2 ± 30.0 |
0.0 (0.0-71.7) |
22 (21.0%) |
n.s.a n.s.b |
| Endrin |
234.2 ± 466.0 |
0.0 (0.0-1553.1) |
24 (49.0%) |
- |
- |
0 (0%) |
n.a.a n.a.b |
| Total Cyclodienes |
256.1 ± 463.6 |
46.5 (0.0-1553.1) |
33 (67.3%) |
83.9 ± 125.2 |
77.5 (0.0-156.7) |
80 (76.2%) |
n.s.a n.s.b |
| p,p-DDE |
275.6 ± 266.2 |
220.8.7 (0.0-653.1) |
46 (93.9%) |
354.5 ± 327.3 |
303.8 (106.1-648.8) |
102 (97.1%) |
n.s.a 0.003b |
| p,p-DDD |
8.6 ± 38.3 |
0.0 (0.0-94.3) |
3 (6.1%) |
412.4 ± 412.1 |
126.5.1 (0.0-1094.7) |
72 (68.6%) |
<0.001a <0.001b |
| p,p-DDT |
324.8 ± 395.5 |
205.4 (0.0-1334.6) |
40 (81.6%) |
153.2 ± 114.0 |
158.7 (0.0-327.3) |
76 (72.4%) |
n.s.a 0.008b |
| Total DDTs |
937.3 ± 824.2 |
706.0 (133.2-3017.4) |
49 (100%) |
1022.7 ± 684.7 |
892.7 (143.0-2225.8) |
105 (100%) |
n.s.a n.s.b |
| Total OCPs | 1210.1 ± 1243.6 | 729.7 (267.9-4570.5) |
49 (100%) | 1156.0 ± 661.1 | 1057.3 (181.7-2364.8) |
105 (100%) | n.s.a 0.043b |
Abbreviations: SD, standard deviation; D, detected compound; p5-p95, percentiles 5 and 95 of the distribution; n.s., non-significant; n.a., not applicable.
aχ2 test.
b Mann–Whitney U-test.