Table 4.
Clinical and endocrine-metabolic parameters with differentLHG1052A genotype andLHRnew SNP genotype in PCOS patients
| LH1052G/G (N=302) | LH1052G/A+A/A (N=13) | LHR wild type (N=246) | LHR mutated type (N=69) | |
|---|---|---|---|---|
| BMI(kg/m2) |
24.243.93 |
22.743.83 |
24.203.91 |
24.154.03 |
| WHR |
0.830.07 |
0.810.05 |
0.830.07 |
0.820.06 |
| Amenorrhea,n(%) |
276(91.39) |
11(84.62) |
223(90.65) |
65(94.20) |
| PCO,n(%) |
282(93.37) |
11(84.62) |
227(92.28) |
66(95.65) |
| LH(mIU/ml) |
9.236.44 |
5.714.07* |
8.856.47 |
9.966.06 |
| FSH(mIU/ml) |
6.211.91 |
5.902.28 |
6.191.97 |
6.231.82 |
| LH/FSH |
1.520.99 |
1.091.06 |
1.471.02 |
1.610.88 |
| Testosterone ( nmol/L) |
1.801.10 |
1.911.04 |
1.791.07 |
1.861.22 |
| A( nmol/L) |
13.665.59 |
13.764.59 |
13.675.50 |
13.635.78 |
| Fasting glucose(mmol/L) |
4.920.63 |
5.321.54* |
4.930.73 |
4.980.60 |
| Fasting insulin(uIU/ml) |
9.706.30 |
13.279.38 |
12.839.13 |
14.249.88 |
| TG(mmol/L) | 1.561.01 | 1.260.49 | 1.550.97 | 1.551.07 |
Independent studentst test and MannWhitney U-test; Data are described in meanSD. P0.05 was considered statistically significant. *: P0.05.