Table 3.
Axial and peripheral spondyloarthritis Assessment of Spondyloarthritis International Society classification criteria
| Axial spondyloarthritis ref. [11] | Peripheral spondyloarthritis ref. [12] | ||
|---|---|---|---|
| Individuals <45 years with back pain >3 months* |
Individuals with arthritis or enthesitis or dactylitis |
||
| Imaging |
HLA-B27 |
||
| Sacroiliitis on MR or X-rays |
Positive test |
||
| Additional features needed for classification§ | |||
| At least one |
At least two |
At least one |
At least two |
| Inflammatory back pain |
Uveitis |
Arthritis |
|
| Arthritis |
Psoriasis |
Enthesitis (heel pain) |
|
| Enthesitis (heel pain) |
Crohn’s/colitis |
Dactylitis |
|
| Uveitis |
Previous infection |
Inflammatory back pain (ever) |
|
| Dactylitis |
HLA-B27 |
Family history for SpA |
|
| Psoriasis |
Sacroiliitis on imaging |
|
|
| Crohn’s/colitis |
|
|
|
| Good response to non-steroidal antinflammatory drugs |
|
|
|
| Family history for spondyloarthritis |
|
|
|
| HLA-B27 |
|
|
|
| Elevated C reactive protein | |||
Classification of individuals as Axial SpA: *Requires two eligibility criteria (age at onset and duration of back pain) followed by two different approaches, one through MR and another through HLA-B27 testing. The former requires at least one and the latter at least two additional criteria.
Classification of individuals as peripheral SpA: Requires at least of three eligibility criteria (arthritis or enthesitis or dactylitis) plus one or two items depending on their diagnostic value.
§Despite axial and peripheral SpA share most additional criteria for classification, the definition of some individual criteria might be different. Please check such definitions in tables.
MR = Magnetic Resonance.