. 2012 May 20;6:45. doi: 10.1186/1752-0509-6-45

Table 2.

Equations describing interactions between intact and partially proteolyzed factor Va with factor Xa and prothrombin

Eqn	Chemical Expression	k_off	k_on	k_dis
Eqn	Chemical Expression	(s^-1)	(M^-1 s^-1)	(s^-1)
11	FXa + FVa ← 7-6 → FXaFVa	0.2 ^a 0.075 ^b	4 x 10^{8 a}
11	FXa + FVa ← 7-6 → FXaFVa	0.2 ^a 0.075 ^b	1.5 x 10^{8 b}
12	FXa + FVa_i⁵⁰⁶ ← 8-6 → FXaFVa_i⁵⁰⁶	0.4 ^c	4 x 10^{8 c}
12	FXa + FVa_i⁵⁰⁶ ← 8-6 → FXaFVa_i⁵⁰⁶	0.15 ^b	1.5 x 10^{8 b}
13	FXa + FVa_i³⁰⁶ ← 8-6 → FXaFVa_i³⁰⁶	0.4 ^c	4 x 10^{8 c}
13	FXa + FVa_i³⁰⁶ ← 8-6 → FXaFVa_i³⁰⁶	0.15 ^b	1.5 x 10^{8 b}
14	FXa + FVa_i^306/506 ← 8-6 → FXaFVa_i^306/506	0.4 ^c	4 x 10^{8 c}
14	FXa + FVa_i^306/506 ← 8-6 → FXaFVa_i^306/506	0.15 ^b	1.5 x 10^{8 b}
15	FXaFVa_i³⁰⁶ -9 → FXa + FVa^1-306FVa^LC + FVa^307-679/709			0.0035
16	FXaFVa_i^306/506 -9 → FXa + FVa^1-306FVa^LC + FVa^307-506 + FVa^507-679/709			0.0035
17	FVa + PT ← 11-10 → FVaPT	70^d	1 x 10⁸

^a Values from previously published studies for mathematical simulations [32,46].

^b Values identified in the current study for mathematical simulations and carried forward through all subsequent mathematical simulations.

^c Values are based on relative findings from previously published studies for mathematical simulations [32].

^d Initial estimate for FVaPT complex from Tran et al. [39].