Table 2.
Pearson correlations between baseline UPSIT, AE, LHCV and APOE and cognitive test scores
| |
All participantsn= 56 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| UP_20 | APOE | LHCV | MMSE | ARCSg | Mem | Flu | Lang | VS | Atten | |
| UPSIT_20 |
1 |
−0.04 |
0.17 |
0.43** |
0.41** |
0.39** |
0.15 |
0.19 |
0.46** |
0.40** |
| AE |
0.06 |
−0.33* |
0.53** |
0.37** |
0.51** |
0.57** |
0.36** |
0.38** |
0.28* |
0.31* |
| LHCV |
0.17 |
−0.12 |
1 |
0.45** |
0.56** |
0.57** |
0.34* |
0.40** |
0.43** |
0.28* |
| |
Non – Dementedn= 42 |
|||||||||
| UPSIT_20 |
1 |
−0.05 |
0.12 |
0.33* |
0.12 |
0.11 |
−0.10 |
−0.02 |
0.25 |
0.17 |
| AE |
−0.15 |
−0.30 |
0.49** |
0.22 |
0.50** |
0.52** |
0.31* |
0.29 |
−0.02 |
0.21 |
| LHCV |
0.12 |
−0.08 |
1 |
0.29 |
0.44** |
0.47** |
0.14 |
0.23 |
0.23 |
0.15 |
| |
ADn= 14 |
|||||||||
| UPSIT_20 |
1 |
0.28 |
−0.53 |
−0.17 |
−0.31 |
−0.04 |
−0.42 |
−0.34 |
−0.07 |
0.18 |
| AE |
−0.05 |
−0.41 |
0.52 |
0.50 |
0.48 |
0.47 |
0.16 |
0.38 |
0.46 |
−0.03 |
| LHCV | −0.53 | −0.16 | 1 | 0.58* | 0.80** | 0.71** | 0.48 | 0.54 | 0.59* | 0.10 |
* P < 0.05; ** P < 0.01; UP_20: Score on 20 items of the 40 item University of Pennsylvania Smell Identification Test (UPSIT_20); AE: Atropine Effect; LHCV: Left hippocampal volume adjusted for intracranial volume; APOE: Apolipoprotein E allele dichotomised (no ϵ4 = 0, any ϵ4 = 1); MMSE: Mini Mental State Examination; ARCSg: Scaled global score on the Audio Recorded Cognitive Screen (ARCS); Mem: Scaled memory domain score on the ARCS; Flu: Scaled fluency domain score on the ARCS; Lang: Scaled language domain score on the ARCS; VS: Scaled visuospatial domain score on the ARCS; Atten: Scaled attention/executive domain score on the ARCS.