Figure 7. Pep24 blocks LFA-1-induced JAB1 relocalization.
Jurkat cells expressing indicated peptides were adhered to either anti-LFA-1 mAb or control IgG coated plates for 30 min. After cross-linking stimulation, cells were stained for JAB1 (red). GFP (green) is an indicator of peptide expression. (A–C) C-Pep1-expressing cells without stimulation. (D–F) C-pep1-expressing cells with LFA-1 cross-linking stimulation. (G–I) Pep24-expressing cells without stimulation. (J–L) Pep24-expressing cells with LFA-1 cross-linking stimulation.
