Table 2. Meta-analyses of CD209 -336A/G promoter polymorphism and risk of TB in each subgroup.
Category | G vs. A | GG vs.AA | Dominant model | Recessive model |
OR (95%CI) I 2 (%) | OR (95%CI) I 2 (%) | OR (95%CI) I 2 (%) | OR (95%CI) I 2 (%) | |
Ethnicity | ||||
African | 1.00 (0.85–1.19) 65 | 1.03 (0.75–1.42) 61 | 1.00 (0.76–1.32) 69 | 0.97 (0.83–1.15) 42 |
Asian | 1.17 (0.71–1.94) 85 | 2.48 (1.46–4.22) 46 | 1.17 (0.71–1.93) 75 | 2.10 (1.33–3.32) 20 |
Caucasian | 1.03 (0.80–1.33) 49 | 0.91 (0.45–1.82) 0 | 1.07 (0.79–1.45) 37 | 0.89 (0.45–1.78) 0 |
Mixed | 1.01 (0.72–1.43) 60 | 1.03 (0.52–2.05) 45 | 0.93 (0.44–1.95) 80 | 1.11 (0.56–2.18) 0 |
Sample types | ||||
PTB | 1.02 (0.88–1.18) 69 | 1.08 (0.79–1.48) 62 | 1.01 (0.83–1.22) 62 | 1.08 (0.85–1.37) 51 |
EPTB | 1.21 (0.84–1.74) 0 | 1.51 (0.58–3.92) 0 | 1.20 (0.77–1.86) 30 | 1.51 (0.59–3.89) 0 |
Abbreviations and definitions: PTB, pulmonary tuberculosis; EPTB, extra-pulmonary tuberculosis; CI, 95% confidence intervals; OR, odds ratio.