Table 2. S. mekongi infection intensity before (D0) and posttreatment (D28) and egg reduction rate for maximum and minimum diagnostic effort.
Treatment | Maximum diagnostic effort (3×3 datasets, n = 64) | Minimum diagnostic effort (1×1 datasets, n = 85) | |||||||||||
Infection intensity | n | # cured | % cured | D0 GM (EPG) | D28 GM (EPG) | ERR (%) | n | # cured | % cured | D0 GM (EPG) | D28 GM (EPG) | ERR (%) | |
40 mg/kg | All infections | 32 | 24 | 75.0 | 21.0 | 0.75 | 96.4 | 21 | 18 | 85.7 | 47.6 | 1.00 | 97.9 |
1–99 EPG | 27 | 20 | 74.1 | 13.1 | 0.81 | 93.8 | 16 | 13 | 81.3 | 22.4 | 1.48 | 93.4 | |
100–399 EPG | 3 | 3 | 100 | 157.1 | 0 | 100 | 2 | 2 | 100 | 200.8 | 0 | 100 | |
≥400 EPG | 2 | 1 | 50.0 | 451.3 | 1.52 | 99.7 | 3 | 3 | 100 | 923.0 | 0 | 100 | |
75 mg/kg | All infections | 26 | 21 | 80.8 | 26.6 | 0.52 | 98.1 | 19 | 18 | 94.7 | 63.5 | 0.23 | 99.6 |
1–99 EPG | 22 | 17 | 77.3 | 18.2 | 0.64 | 96.5 | 14 | 13 | 92.9 | 45.1 | 0.32 | 99.3 | |
100–399 EPG | 4 | 4 | 100 | 201.7 | 0 | 100 | 5 | 5 | 100 | 163.6 | 0 | 100 | |
≥400 EPG | 0 | 0 | na | na | na | na | 0 | 0 | na | na | na | na |
EPG, eggs per gram of stool; ERR, egg reduction rate; GM, geometric mean; na, not applicable.