Table 3. O. viverrini infection intensity before (D0) and posttreatment (D28) and egg reduction rate for maximum and minimum diagnostic effort.
Treatment | Maximum diagnostic effort (3×3 datasets, n = 64) | Minimum diagnostic effort (1×1 datasets, n = 85) | |||||||||||
Infection intensity | n | # cured | % cured | D0 GM (EPG) | D28 GM (EPG) | ERR (%) | n | # cured | % cured | D0 GM (EPG) | D28 GM (EPG) | ERR (%) | |
40 mg/kg | All infections | 35 | 25 | 71.4 | 307.4 | 0.99 | 99.7 | 35 | 33 | 94.3 | 411.8 | 0.26 | 99.94 |
1–999 EPG | 24 | 18 | 75.0 | 96.4 | 0.48 | 99.5 | 24 | 24 | 100 | 142.3 | 0 | 100 | |
1,000–9,999 EPG | 9 | 6 | 66.7 | 2,460 | 2.1 | 99.92 | 9 | 7 | 77.8 | 2,817 | 1.4 | 99.95 | |
≥10,000 EPG | 2 | 1 | 50.0 | 27,344 | 9.0 | 99.97 | 2 | 2 | 100 | 23,778 | 0 | 100 | |
75 mg/kg | All infections | 29 | 28 | 96.6 | 308.1 | 0.05 | 99.98 | 35 | 35 | 100 | 383.7 | 0 | 100 |
1–999 EPG | 20 | 20 | 100 | 103.7 | 0.00 | 100 | 24 | 24 | 100 | 181.1 | 0 | 100 | |
1,000–9,999 EPG | 9 | 8 | 88.9 | 3,424.2 | 0.16 | 100 | 10 | 10 | 100 | 1,568 | 0 | 100 | |
≥10,000 EPG | 0 | 0 | na | na | na | na | 1 | 1 | 100 | 18,816 | 0 | 100 |
EPG, eggs per gram of stool; ERR, egg reduction rate; GM, geometric mean; na, not applicable.