Figure 7. Effect of a p38 MAP kinase inhibitor on cytokine (A–C), chemokine (D,E) and amphiregulin (F) concentration in bronchoalveolar fluid in high pressure ventilated BALB/c mice.

All lungs were subjected to HPV. Lung lavage fluid was obtained from the right lung after 240 min of ventilation and analyzed by ELISA for IL6 (A), Il1b (B), TNF (C), CXCL1 aka KC (D), CXCL2 aka MIP-2α (E) and amphiregulin (E). LPV, vehicle (DMSO); HPV, SB203580. Data are mean + SEM with n = 6 per study group.