Figure 4. The crystal structure of T. brucei ornithine decarboxylase, TbODC (PDB 1njj) [53].

The docked poses are the biflavonoids GB1a (magenta), GB2 (yellow), GB3 (green) and kolaflavanone (brown). The co-crystallized ligands are geneticin (green wire figure) and pyridoxylphosphate/d-ornithine (yellow wire figure).