Table 3.

Adjusted relative hazards of incident AF related to serum uric acid.

SUA measurement		Model A	Model B	Model C	Model D
Baseline (visit 1)	HR†	1.30	1.25	1.16	1.07
	95% CI	1.21, 1.40	1.15, 1.36	1.06,1.26	0.97, 1.17
	p-value	<0.01	<0.01	<0.01	0.12
Mean value	HR	1.24	1.20	1.14	1.07
	95% CI	1.18,1.31	1.13,1.27	1.08,1.21	1.01,1.14
	p-value	<0.01	<0.01	<0.01	<0.01
Time varying	HR	1.29	1.27	1.24	1.18
	95% CI	1.02,1.63	1.00,1.63	0.97,1.57	0.95,1.48
	p-value	0.03	0.04	0.07	0.12

^†HR: hazard ratio indicates adjusted relative hazards per standard deviation (SD) of serum uric acid difference at visit 1 (SD= 1.56 mg/dl).

Model A adjusts simultaneously for age, sex, race, education and field center.

Model B adjusts simultaneously for all variables in model A as well as, body mass index, alcohol use, serum glucose, systolic and diastolic blood pressure, and LDL-cholesterol.

Model C adjusts simultaneously for all variables in model B as well as, prevalent coronary heart disease and heart failure, serum creatinine, use of diuretics and p wave duration on ECG at baseline.

Model D adjusts for Model C, and censors individuals when they develop incident myocardial infarction or heart failure.