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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: Biomaterials. 2012 Jul 9;33(28):6783–6792. doi: 10.1016/j.biomaterials.2012.05.068

Figure 9.

Figure 9

Biobrane functionalized with CX/PEMs promoted normal healing in ‘full-thickness’ splinted dermal wounds (6 mm diameter) in normal wild-type mice. Digital images showing simple, gross observation of wound healing on post-operative days 0, 7 and 14, respectively, in groups treated with: (A, B, C) Biobrane, or (D, E, F) Biobrane functionalized with PEMs of (PAH/PAA)10(PS microspheres)(CX/PAA)80. (G) Percentage of original wound size on post-operative days 3, 7, 10 and 14 in groups treated with either Biobrane functionalized with CX/PEMs, or unmodified Biobrane. Each data point presents mean ± SEM of relative wound size (n≥5 mice). Results show that CX/PEMs do not impair the adherence of the dressing to the wounds (as seen from gross images), nor the rate of wound closure.