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Summary of the Cellular and Molecular Alterations That Affect the Intestinal Barrier Function in IBS
IBS, irritable bowel syndrome; MLCK, myosin light chain kinase; MLC, myosin light chain; TJ, tight junction; TNF-α, tumor necrosis factor alpha; IFN-γ, interferon gamma; ZO, zonula occludens; PAR-2, protease-activated receptor 2; MBP, major basic protein; IBS-D, diarrhea-predominant irritable bowel syndrome.
