Table 2.
Differences in micronucleus (MN) frequency by VCM exposure.
CED (mg/m3) | Number | MN Freq ± SE (‰) | FR (95%CI) |
---|---|---|---|
Control | 30 | 1.60 ± 1.30 | 1 |
Exposure | 317 | 3.47 ± 2.65** | 2.31(1.81–3.01) |
0~ | 76 | 3.16 ± 2.50** | 2.07(1.61–2.83) |
0.48~ | 71 | 2.68 ± 2.31** | 1.80(1.36–2.41) |
1.13~ | 87 | 3.62 ± 2.65** | 2.43(1.86–3.23) |
6.36~ | 83 | 4.29 ± 2.84** | 2.88(2.21–3.82) |
MN, micronuclei; FR, frequency ratio, compare with pooled unexposed and control group MN; VCM, vinyl chloride monomer; ‰, per thousand lymphocytes; SD, standard deviation; CED, cumulative exposure dose, VCM exposed subjects were divided into four groups with quarte cumulative doses.
Compare with control group P < 0.01.