Fig. 4.

Evaluation of AR in lung cancer cells. A, Lung cancer cell growth response to DHT treatment. Relative growth responses were assessed as described in Materials and Methods. Asterisks show the statistically significant points evaluated by ANOVA. B, Hierarchical clustering of AR-dependent gene signatures and lung cancer cells. A genetic signature of 380 genes showing more than a 2-fold difference between AR-positive and AR-negative lung cancer cells was used for the cluster analysis using Matrix 1.29.