Table 3.
Representative pituitary genes involved in stem cell regulations, regulation of invasion, tumor recurrence, and drug resistance
| Gene symbol | Gene title | Fold | P value |
|---|---|---|---|
| Gale | UDP-galactose-4-epimerase | 12.3 | 1.1E-04 |
| G6pd | Glucose-6-phosphate dehydrogenase | 2.9 | 1.6E-04 |
| Efs | Embryonal Fyn-associated substrate | −4.0 | 2.3E-04 |
| Ccr5 | Chemokine (C-C motif) receptor 5 | 22.7 | 4.1E-04 |
| Dcn | Decorin | −20.3 | 4.6E-04 |
| Cd68 | Cd68 molecule | 5.1 | 5.8E-04 |
| Il4ra | IL-4 receptor, α | 28.6 | 6.8E-04 |
| Cd14 | CD14 molecule | 4.3 | 8.2E-04 |
| Cd44 | Cd44 molecule | 2.9 | 8.5E-04 |
| Cad | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase | 3.0 | 1.0E-03 |
| Abr | Active BCR-related gene | −2.1 | 1.1E-03 |
| Cd55 | Cd55 molecule | 18.5 | 1.3E-03 |
| Crop | Cisplatin resistance-associated overexpressed protein | −2.0 | 1.3E-03 |
| Dlk1 | δ-Like 1 homolog (Drosophila) | −4.4 | 1.3E-03 |
| Spn | Sialophorin | −2.6 | 1.4E-03 |
| Mdm2 | Mdm2 p53 binding protein homolog (mouse) | 1.5 | 1.8E-03 |
| Notch2 | Notch homolog 2 (Drosophila) | −4.9 | 1.9E-03 |
| Numb | Numb homolog (Drosophila) | −1.6 | 2.1E-03 |
| Cd9 | CD9 molecule | −2.0 | 2.2E-03 |
| Lox | Lysyl oxidase | 6.1 | 2.3E-03 |
| Evi1 | Ecotropic viral integration site 1 | −3.0 | 2.3E-03 |
| Ace | Angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | −5.4 | 2.5E-03 |
| App | Amyloid β (A4) precursor protein | 2.1 | 2.6E-03 |
| Anxa5 | Annexin A5 | 1.6 | 2.6E-03 |
| Tnfrsf11a | TNF receptor superfamily, member 11a | 10.4 | 2.7E-03 |
| Ptpn11 | Protein tyrosine phosphatase, nonreceptor type 11 | −1.7 | 2.8E-03 |
| Ky | Kyphoscoliosis peptidase | −4.2 | 3.2E-03 |
| Hmox1 | Heme oxygenase (decycling) 1 | 9.5 | 3.6E-03 |
| Hes1 | Hairy and enhancer of split 1 (Drosophila) | −1.8 | 3.7E-03 |
| Dcx | Doublecortin | −4.3 | 3.9E-03 |
| Cdk4 | Cyclin-dependent kinase 4 | 1.6 | 4.1E-03 |
| Ptpn6 | Protein tyrosine phosphatase, nonreceptor type 6 | 1.4 | 4.1E-03 |
| Sp1 | Sp1 transcription factor | 2.1 | 4.5E-03 |
| Rars | Arginyl-tRNA synthetase | 1.7 | 4.7E-03 |
| Itgb2 | Integrin-β2 | 1.9 | 4.8E-03 |
| Bcr | Breakpoint cluster region | −1.4 | 5.0E-03 |
| Dhfr | Dihydrofolate reductase | 1.8 | 6.0E-03 |
| Lef1 | Lymphoid enhancer binding factor 1 | −1.9 | 6.6E-03 |
| Ckap4 | Cytoskeleton-associated protein 4 | 3.9 | 6.9E-03 |
| Stat1 | Signal transducer and activator of transcription 1 | −1.7 | 7.5E-03 |
| Ptprc | Protein tyrosine phosphatase, receptor type, C | 13.3 | 8.3E-03 |
| Pten | Phosphatase and tensin homolog | 2.3 | 8.8E-03 |
| Sox2 | SRY (sex determining region Y)-box 2 | −2.3 | 9.0E-03 |
| Bdnf | Brain derived neurotrophic factor | 11.4 | 9.6E-03 |
| Rad51 | RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) | 2.1 | 9.6E-03 |
| Wars | Tryptophanyl-tRNA synthetase | 1.7 | 9.6E-03 |
| Cdc42 | Cell division cycle 42 (GTP binding protein) | 1.2 | 9.6E-03 |
| Ril | Reversion induced LIM gene | −2.2 | 9.7E-03 |
| Rac1 | Ras-related C3 botulinum toxin substrate 1 | 2.0 | 9.8E-03 |