Table 3.

Prospective studies of sugar-sweetened beverages and pancreatic cancer

Author (reference)	Study design	Study population	Incident cases; length follow-up	Findings
Schernhammer et al. (24)	Prospective cohort analysis	2 U.S. cohorts: 138,158 U.S. nurses and other health professionals; females ages 30–55 y and males ages 40–75 y	Total cohort: 379 cases; 20 y follow-up Females: 205 cases; 20 y follow-up Males: 174 cases; 20 y follow-up	Women who consumed >3 servings sugar-sweetened soft drink/wk had elevated risk of pancreatic cancer (HR, 1.57; 95% CI, 1.02–2.41), but no association observed in males
Larsson et al. (25)	Prospective cohort analysis	77,797 Swedish nurses and other health professionals ages 45–83 y	Total cohort: 131 cases; 7.2 y follow-up	Elevated risk of pancreatic cancer for ≥2 glasses total soft drink/d (HR, 1.93; 95% CI, 1.18–3.14)
Nothlings et al. (26)	Prospective cohort analysis	Multiethnic Cohort Study: 162,150 healthy women and men in Hawaii-Los Angeles ages 45–75 y	Total cohort: 434 cases; 8 y follow-up	No association between soft drink or juice intake and pancreatic cancer but elevated risk for highest category of juice and fruit combined intake (HR, 1.37; 95% CI, 1.02–1.84)
Bao et al. (27)	Prospective cohort analysis	AARP Diet and Health Study: 487,922 U.S. healthy men and women ages 50–71 y	Total cohort: 1258 cases; 7.2 y follow-up	No association between soft drink or juice intake and pancreatic cancer