Table 1.
Survival of L. plantarum (LP)-primed BALB/c mice inoculated with PVM on day 0 as per standard protocol [Fig. 1A] or delayed seven, twenty-one or ninety-one days thereafter. Survival was determined at t = 30 days after each virus inoculation. All surviving mice (29 of a total 34) underwent seroconversion to PVM antigens (SMART-M12, see Methods).
| Virus inoculation on | day 0 | day 7 | day 21 | day 91 |
|---|---|---|---|---|
| Survival | 8/8 (100%) | 7/8a (88%) | 8/8 (100%) | 6/10 (60%) |
a
The single death among the mice inoculated on day 7 occurred 8 days after PVM inoculation. The full survival analysis of the mice inoculated 91 days after Lactobacillus priming is shown in Figure 1D.