Fig. 4.

Comparison of responses of BALB/c mice to three component sequential and two-stage mixed-component regimes. Vaccination regimes were as described in legend to Fig. 3 with doses as in legend to Fig. 1. This permitted all results depicted in this figure to be obtained from synchronous assays 14 days after final vaccination. Data for groups A–M–P and A–P–M are as displayed in Fig. 3, repeated here for clarity. Panel A: Total IgG responses assessed by ELISA. Panel B: IFNγ⁺ CD8⁺ T cell responses assessed by ICS.