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. Author manuscript; available in PMC: 2012 Jul 25.
Published in final edited form as: Virology. 2009 Jun 18;390(2):338–347. doi: 10.1016/j.virol.2009.05.030

Figure 2. Comparison of BeAr436087 and FL93-939 replication and dissemination.

Figure 2

6-week-old CD1 mice were infected with 103 pfu of BeAr436087 (open circle) or FL93-939 (closed circle) in each hind footpad. Mice were perfused with PBS-1% DCS prior to tissue harvesting, homogenization and mechanical disruption. Virus titers in serum and tissue homogenates were determined by BHK-21 plaque titration: A) popliteal draining lymph node; B) serum; C) spleen; D) knee joint (femur epiphyses and metaphyses); E) bone aspirate (femur); F) brain. LD = limit of detection of the plaque assay and error bars represent standard deviations.