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. Author manuscript; available in PMC: 2013 Jun 1.
Published in final edited form as: Lancet Infect Dis. 2012 Mar 23;12(6):457–468. doi: 10.1016/S1473-3099(12)70055-5

Figure 2.

Figure 2

Unadjusted individual and summary Odds Ratios for specific malaria syndromes by haemoglobin variants

Abbreviations: CI, confidence interval; Hb, haemoglobin

a Not included in meta-analyses because prevalences of HbAS in cases and controls were not reported. All Odds Ratios (ORs) are for comparison with healthy controls. The data markers represent either ORs from individual studies (circles) or summary ORs for subgroup data (diamonds) that were generated by random-effects meta-analysis of individual studies (squares). For individual studies included in meta-analyses, the size of the square data marker is relative to the weight of the study. The I2 statistic is a measure of the heterogeneity of the individual study estimates which were meta-analyzed, and was calculated using the Mantel-Haenszel method. ORs for individual studies may differ from those in Table S1 or in the original published studies because they were calculated from raw data and are thus unadjusted.