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. 2012 Apr 25;303(2):C143–C150. doi: 10.1152/ajpcell.00062.2012

Fig. 8.

Fig. 8.

Slo channel in hair cells show increased clustering in response to PKC activation. Hair cells in culture were treated with PMA for 3 h and Slo detected by immunofluorescence. Shown are confocal images in the X-Y plane of representative basilar papillae. Hair cells in chick cochlea treated with PMA (B) and monensin (C) show an increase in BK channel clusters compared with hair cells of control cochlea (A). D: shown are the number of BK channel clusters in hair cells from cochlea treated with 100 nM PMA and 2 μM monensin. There is a statistically significant increase in BK channel clusters in hair cells of cochlea treated with PMA and separately monensin compared with controls (P < 0.01 on 1-way ANOVA; n = 3 samples each).