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A: cholesterol depletion with methyl-β-cyclodextrin (MBCD) in control ECs caused enhanced outward current compared with untreated control ECs that was reversed by HO blockade with ZnPPIX. *P < 0.05 vs. control treatment (−40 to +150 mV); δP < 0.05 vs. MBCD (−20 to +150 mV). B: summarized data at −40 mV. *Different from the vehicle-treated control cells; δdifferent from control cells treated with MBCD.
